Case report and cohort analysis of drug-induced liver injury associated with daptomycin.

نویسندگان

  • Nicole Bohm
  • Charles Makowski
  • Mario Machado
  • Adam Davie
  • Nelson Seabrook
  • Lee Wheless
  • Benjamin Bevill
  • Bradley Clark
  • T Rogers Kyle
چکیده

A patient receiving daptomycin developed asymptomatic transaminitis and hyperbilirubinemia without concurrent multiorgan dysfunction or elevation of his creatinine kinase level. After ruling out other etiologies, the liver injury was attributed to daptomycin and was subsequently resolved. A single-center retrospective cohort analysis of baseline and follow-up liver function panels (n = 614) from all admissions from 2008 to 2013 during which daptomycin was administered did not reveal any other cases of probable or definite drug-induced liver injury associated with daptomycin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 58 8  شماره 

صفحات  -

تاریخ انتشار 2014